Axsome Therapeutics Stock Analysis

AXSM Stock  USD 182.35  0.59  0.32%   
Below is the normalized historical share price chart for Axsome Therapeutics extending back to November 19, 2015. This chart has been adjusted for all splits and dividends and is plotted against all major global economic recessions. As of today, the current price of Axsome Therapeutics stands at 182.35, as last reported on the 13th of February 2026, with the highest price reaching 182.35 and the lowest price hitting 182.35 during the day.
IPO Date
19th of November 2015
200 Day MA
129.1476
50 Day MA
166.7359
Beta
0.402
 
Yuan Drop
 
Covid
 
Interest Hikes
Axsome Therapeutics has over 192.96 Million in debt which may indicate that it relies heavily on debt financing. At this time, Axsome Therapeutics' Debt To Assets are very stable compared to the past year. As of the 13th of February 2026, Total Debt To Capitalization is likely to grow to 1.01, while Short and Long Term Debt is likely to drop about 2.2 M. Axsome Therapeutics' financial risk is the risk to Axsome Therapeutics stockholders that is caused by an increase in debt.

Asset vs Debt

Equity vs Debt

Axsome Therapeutics' liquidity is one of the most fundamental aspects of both its future profitability and its ability to meet different types of ongoing financial obligations. Axsome Therapeutics' cash, liquid assets, total liabilities, and shareholder equity can be utilized to evaluate how much leverage the Company is using to sustain its current operations. For traders, higher-leverage indicators usually imply a higher risk to shareholders. In addition, it helps Axsome Stock's retail investors understand whether an upcoming fall or rise in the market will negatively affect Axsome Therapeutics' stakeholders.
For many companies, including Axsome Therapeutics, marketable securities, inventories, and receivables are the most common assets that could be converted to cash. However, for Axsome Therapeutics, the most critical issue when managing liquidity is ensuring that current assets are properly aligned with current liabilities. If they are not, Axsome Therapeutics' management will need to obtain alternative financing to ensure there are always enough cash equivalents on the balance sheet to meet obligations.
Price Book
126.0196
Enterprise Value Ebitda
(14.81)
Price Sales
16.7092
Shares Float
42.5 M
Wall Street Target Price
215.441
At this time, Axsome Therapeutics' Liabilities And Stockholders Equity is very stable compared to the past year. As of the 13th of February 2026, Other Stockholder Equity is likely to grow to about 1.4 B, while Common Stock Total Equity is likely to drop 2,748. . At this time, Axsome Therapeutics' Price Book Value Ratio is very stable compared to the past year. As of the 13th of February 2026, Price To Book Ratio is likely to grow to 67.19, while Price Earnings Ratio is likely to drop (13.34).
Axsome Therapeutics is undervalued with Real Value of 194.53 and Target Price of 215.44. The main objective of Axsome Therapeutics stock analysis is to determine its intrinsic value, which is an estimate of what Axsome Therapeutics is worth, separate from its market price. There are two main types of Axsome Therapeutics' stock analysis: fundamental analysis and technical analysis.
The Axsome Therapeutics stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA. Axsome Therapeutics is usually not traded on Labour Day, Thanksgiving Day, Christmas Day, New Year 's Day, Dr . Martin Luther King Jr 's Birthday, Washington 's Birthday, Good Friday, Memorial Day, Juneteenth Holiday, Independence Day ( substitute day ), Independence Day. Axsome Stock trading window is adjusted to America/New York timezone.
Check out Trending Equities to better understand how to build diversified portfolios, which includes a position in Axsome Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in producer price index.
To learn how to invest in Axsome Stock, please use our How to Invest in Axsome Therapeutics guide.

Axsome Stock Analysis Notes

About 16.0% of the company shares are held by company insiders. The company recorded a loss per share of 4.67. Axsome Therapeutics had not issued any dividends in recent years. Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system disorders in the United States. The company was incorporated in 2012 and is based in New York, New York. Axsome Thera operates under Biotechnology classification in the United States and is traded on NASDAQ Exchange. It employs 198 people. For more info on Axsome Therapeutics please contact Herriot MD at 212 332 3241 or go to https://www.axsome.com.

Axsome Therapeutics Investment Alerts

Axsome Therapeutics had very high historical volatility over the last 90 days
The company reported the previous year's revenue of 385.69 M. Net Loss for the year was (287.22 M) with profit before overhead, payroll, taxes, and interest of 515.6 M.
Axsome Therapeutics currently holds about 73.39 M in cash with (128.41 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 1.82.
Axsome Therapeutics has a frail financial position based on the latest SEC disclosures
Over 78.0% of the company shares are held by institutions such as insurance companies
Latest headline from MacroaxisInsider: Disposition of 5193 shares by Coleman Mark of Axsome Therapeutics at 8.02 subject to Rule 16b-3

Axsome Largest EPS Surprises

Earnings surprises can significantly impact Axsome Therapeutics' stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2018-08-08
2018-06-30-0.29-0.32-0.0310 
2016-05-11
2016-03-31-0.28-0.31-0.0310 
2017-08-09
2017-06-30-0.34-0.30.0411 
View All Earnings Estimates

Axsome Therapeutics Environmental, Social, and Governance (ESG) Scores

Axsome Therapeutics' ESG score is a quantitative measure that evaluates Axsome Therapeutics' performance and commitment regarding environmental, social, and governance (ESG) factors. These scores are becoming increasingly crucial in investment decision-making processes, providing insights into non-financial aspects of Axsome Therapeutics' operations that may have significant financial implications and affect Axsome Therapeutics' stock price as well as guide investors towards more socially responsible investments.

Axsome Stock Institutional Investors

Institutional investors include commercial and private banks, credit unions, insurance companies, pension funds, hedge funds, endowments, and mutual funds. Operating companies that invest excess capital in these types of assets may also be included in the term and may influence corporate governance by exercising voting rights in their investments.
Shares
Eventide Asset Management, Llc2025-06-30
725.7 K
Wellington Management Company Llp2025-06-30
725 K
Alethea Capital Management, Llc2025-06-30
667.4 K
T. Rowe Price Associates, Inc.2025-06-30
612.7 K
Ubs Group Ag2025-06-30
595.5 K
Amvescap Plc.2025-06-30
571.5 K
Man Group Plc2025-06-30
525.1 K
Partner Fund Management Lp2025-06-30
483.1 K
Norges Bank2025-06-30
468.3 K
Vanguard Group Inc2025-06-30
3.9 M
Blackrock Inc2025-06-30
3.8 M
Note, although Axsome Therapeutics' institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Axsome Market Capitalization

The company currently falls under 'Mid-Cap' category with a current market capitalization of 9.38 B.

Axsome Profitablity

The company has Profit Margin (PM) of (0.41) %, which may suggest that it does not properly executes on its current pricing strategies or is unable to control all of the operational costs. This is way below average. Similarly, it shows Operating Margin (OM) of (0.19) %, which suggests for every $100 dollars of sales, it generated a net operating loss of $0.19.
Last ReportedProjected for Next Year
Return On Tangible Assets(0.51)(0.53)
Return On Capital Employed(0.75)(0.78)
Return On Assets(0.45)(0.48)
Return On Equity(5.79)(6.08)

Management Efficiency

Axsome Therapeutics has return on total asset (ROA) of (0.1979) % which means that it has lost $0.1979 on every $100 spent on assets. This is way below average. Similarly, it shows a return on stockholder's equity (ROE) of (2.755) %, meaning that it created substantial loss on money invested by shareholders. Axsome Therapeutics' management efficiency ratios could be used to measure how well Axsome Therapeutics manages its routine affairs as well as how well it operates its assets and liabilities. As of the 13th of February 2026, Return On Tangible Assets is likely to drop to -0.53. In addition to that, Return On Capital Employed is likely to drop to -0.78. At this time, Axsome Therapeutics' Other Assets are very stable compared to the past year. As of the 13th of February 2026, Intangibles To Total Assets is likely to grow to 0.15, while Return On Tangible Assets are likely to drop (0.53).
Last ReportedProjected for Next Year
Book Value Per Share 1.07  1.47 
Tangible Book Value Per Share(0.04)(0.03)
Enterprise Value Over EBITDA(12.98)(13.63)
Price Book Value Ratio 63.99  67.19 
Enterprise Value Multiple(12.98)(13.63)
Price Fair Value 63.99  67.19 
Enterprise Value3.1 B3.2 B
Leadership at Axsome Therapeutics emphasizes sustainable growth and financial prudence. Our analysis evaluates how these priorities impact the stock's performance in the market.
Operating Margin
(0.19)
Profit Margin
(0.41)
Beta
0.402
Return On Assets
(0.20)
Return On Equity
(2.75)

Technical Drivers

As of the 13th of February 2026, Axsome Therapeutics shows the Downside Deviation of 1.71, mean deviation of 1.83, and Risk Adjusted Performance of 0.1227. Axsome Therapeutics technical analysis gives you the methodology to make use of historical prices and volume patterns to determine a pattern that approximates the direction of the firm's future prices. Please confirm Axsome Therapeutics standard deviation, maximum drawdown, as well as the relationship between the Maximum Drawdown and expected short fall to decide if Axsome Therapeutics is priced correctly, providing market reflects its regular price of 182.35 per share. Given that Axsome Therapeutics has jensen alpha of 0.4783, we suggest you to validate Axsome Therapeutics's prevailing market performance to make sure the company can sustain itself at a future point.

Axsome Therapeutics Price Movement Analysis

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Axsome Therapeutics Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Axsome Therapeutics insiders, such as employees or executives, is commonly permitted as long as it does not rely on Axsome Therapeutics' material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Axsome Therapeutics insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.
 
Coleman Mark 3 days ago
Disposition of 5193 shares by Coleman Mark of Axsome Therapeutics at 8.02 subject to Rule 16b-3
 
Pizzie Nick over two weeks ago
Disposition of 12000 shares by Pizzie Nick of Axsome Therapeutics at 187.92 subject to Rule 16b-3
 
Mark Jacobson over three weeks ago
Disposition of 15000 shares by Mark Jacobson of Axsome Therapeutics at 4.85 subject to Rule 16b-3
 
Tabuteau Herriot over three months ago
Disposition of 19220 shares by Tabuteau Herriot of Axsome Therapeutics at 120.17 subject to Rule 16b-3
 
Mark Jacobson over three months ago
Disposition of 10000 shares by Mark Jacobson of Axsome Therapeutics at 115.96 subject to Rule 16b-3
 
Tabuteau Herriot over three months ago
Disposition of 19719 shares by Tabuteau Herriot of Axsome Therapeutics at 114.19 subject to Rule 16b-3
 
Jeffs Roger over three months ago
Disposition of 16694 shares by Jeffs Roger of Axsome Therapeutics at 120.08 subject to Rule 16b-3
 
Murdock Hunter R. over six months ago
Disposition of 6014 shares by Murdock Hunter R. of Axsome Therapeutics at 100.12 subject to Rule 16b-3
 
Murdock Hunter R. over six months ago
Disposition of 7500 shares by Murdock Hunter R. of Axsome Therapeutics at 100.26 subject to Rule 16b-3
 
Coleman Mark over six months ago
Disposition of 3000 shares by Coleman Mark of Axsome Therapeutics at 107.491 subject to Rule 16b-3
 
Tabuteau Herriot over six months ago
Acquisition by Tabuteau Herriot of 28887 shares of Axsome Therapeutics at 137.75 subject to Rule 16b-3
 
Coleman Mark over a year ago
Acquisition by Coleman Mark of 500 shares of Axsome Therapeutics at 58.15 subject to Rule 16b-3

Axsome Therapeutics Outstanding Bonds

Axsome Therapeutics issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Axsome Therapeutics uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Axsome bonds can be classified according to their maturity, which is the date when Axsome Therapeutics has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Axsome Therapeutics Predictive Daily Indicators

Axsome Therapeutics intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Axsome Therapeutics stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Axsome Therapeutics Corporate Filings

F4
10th of February 2026
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
F4
2nd of February 2026
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
F4
23rd of January 2026
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
8K
12th of January 2026
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
F4
7th of January 2026
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
F4
2nd of January 2026
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
8K
31st of December 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
F4
4th of December 2025
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify

Axsome Therapeutics Forecast Models

Axsome Therapeutics' time-series forecasting models are one of many Axsome Therapeutics' stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Axsome Therapeutics' historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

Axsome Therapeutics Bond Ratings

Axsome Therapeutics financial ratings play a critical role in determining how much Axsome Therapeutics have to pay to access credit markets, i.e., the amount of interest on their issued debt. The threshold between investment-grade and speculative-grade ratings has important market implications for Axsome Therapeutics' borrowing costs.
Piotroski F Score
2
FrailView
Beneish M Score
(3.39)
Unlikely ManipulatorView

Axsome Therapeutics Debt to Cash Allocation

Many companies such as Axsome Therapeutics, eventually find out that there is only so much market out there to be conquered, and adding the next product or service is only half as profitable per unit as their current endeavors. Eventually, the company will reach a point where cash flows are strong, and extra cash is available but not fully utilized. In this case, the company may start buying back its stock from the public or issue more dividends.
Axsome Therapeutics currently holds 192.96 M in liabilities with Debt to Equity (D/E) ratio of 6.2, indicating the company may have difficulties to generate enough cash to satisfy its financial obligations. Axsome Therapeutics has a current ratio of 2.39, suggesting that it is liquid enough and is able to pay its financial obligations when due. Note, when we think about Axsome Therapeutics' use of debt, we should always consider it together with its cash and equity.

Axsome Therapeutics Total Assets Over Time

Axsome Therapeutics Assets Financed by Debt

The debt-to-assets ratio shows the degree to which Axsome Therapeutics uses debt to finance its assets. It includes both long-term and short-term borrowings maturing within one year. It also includes both tangible and intangible assets, such as goodwill.

Axsome Therapeutics Debt Ratio

    
  63.0   
It appears that about 37% of Axsome Therapeutics' assets are financed be debt. Typically, companies with high debt-to-asset ratios are said to be highly leveraged. The higher the ratio, the greater risk will be associated with the Axsome Therapeutics' operation. In addition, a high debt-to-assets ratio may indicate a low borrowing capacity of Axsome Therapeutics, which in turn will lower the firm's financial flexibility.

Axsome Therapeutics Corporate Bonds Issued

Axsome Therapeutics issues bonds to finance its operations. Corporate bonds make up one of the most significant components of the U.S. bond market and are considered the world's largest securities market. Axsome Therapeutics uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt.

Axsome Short Long Term Debt Total

Short Long Term Debt Total

232.99 Million

At this time, Axsome Therapeutics' Short and Long Term Debt Total is very stable compared to the past year.

About Axsome Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Axsome Therapeutics prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Axsome shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Axsome Therapeutics. By using and applying Axsome Stock analysis, traders can create a robust methodology for identifying Axsome entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(0.67)(0.70)
Operating Profit Margin(0.65)(0.69)
Net Loss(0.67)(0.70)
Gross Profit Margin 0.82  0.72 

Current Axsome Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Axsome analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Axsome analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceConsensus# of Analysts
215.44Strong Buy19Odds
Axsome Therapeutics current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Axsome analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Axsome stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Axsome Therapeutics, talking to its executives and customers, or listening to Axsome conference calls.
Axsome Analyst Advice Details

Axsome Stock Analysis Indicators

Axsome Therapeutics stock analysis indicators help investors evaluate how Axsome Therapeutics stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Axsome Therapeutics shares will generate the highest return on investment. By understating and applying Axsome Therapeutics stock analysis, traders can identify Axsome Therapeutics position entry and exit signals to maximize returns.
Begin Period Cash Flow386.2 M
Long Term Debt180.7 M
Common Stock Shares Outstanding47.9 M
Total Stockholder Equity57 M
Total Cashflows From Investing Activities-270 K
Tax Provision85 K
Property Plant And Equipment NetM
Cash And Short Term Investments315.4 M
Cash315.4 M
Accounts Payable72 M
Net Debt-122.4 M
50 Day M A166.7359
Total Current Liabilities230.1 M
Other Operating Expenses666.3 M
Non Current Assets Total83.4 M
Forward Price Earnings333.3333
Non Currrent Assets Other18.5 M
Stock Based Compensation85.2 M
When determining whether Axsome Therapeutics is a strong investment it is important to analyze Axsome Therapeutics' competitive position within its industry, examining market share, product or service uniqueness, and competitive advantages. Beyond financials and market position, potential investors should also consider broader economic conditions, industry trends, and any regulatory or geopolitical factors that may impact Axsome Therapeutics' future performance. For an informed investment choice regarding Axsome Stock, refer to the following important reports:
Check out Trending Equities to better understand how to build diversified portfolios, which includes a position in Axsome Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in producer price index.
To learn how to invest in Axsome Stock, please use our How to Invest in Axsome Therapeutics guide.
You can also try the Stocks Directory module to find actively traded stocks across global markets.
Will Pharmaceuticals sector continue expanding? Could Axsome diversify its offerings? Factors like these will boost the valuation of Axsome Therapeutics. If investors know Axsome will grow in the future, the company's valuation will be higher. Accurate valuation requires analyzing both current fundamentals and future growth trajectories. Every Axsome Therapeutics data point contributes insight, yet successful analysis hinges on identifying the most consequential variables.
Earnings Share
(4.67)
Revenue Per Share
11.402
Quarterly Revenue Growth
0.632
Return On Assets
(0.20)
Return On Equity
(2.75)
Investors evaluate Axsome Therapeutics using market value (trading price) and book value (balance sheet equity), each telling a different story. Calculating Axsome Therapeutics' intrinsic value - the estimated true worth - helps identify when the stock trades at a discount or premium to fair value. Seasoned market participants apply comprehensive analytical frameworks to derive fundamental worth and identify mispriced opportunities. External factors like market trends, sector rotation, and investor psychology can cause Axsome Therapeutics' market price to deviate significantly from intrinsic value.
Understanding that Axsome Therapeutics' value differs from its trading price is crucial, as each reflects different aspects of the company. Evaluating whether Axsome Therapeutics represents a sound investment requires analyzing earnings trends, revenue growth, technical signals, industry dynamics, and expert forecasts. Conversely, Axsome Therapeutics' market price signifies the transaction level at which participants voluntarily complete trades.